Introducing 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid: A Versatile Compound for Advanced Applications

CAS Number: 162401-62-9
Synonyms: 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid; 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic Acid; Roflumilast Impurity 1

Product Overview

3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid is a specialized chemical compound with remarkable potential in pharmaceuticals, particularly as an impurity profile component in high-value drugs, notably Roflumilast. With its unique structural features, this compound offers exceptional stability and reactivity, making it an essential intermediate in the synthesis of various bioactive molecules.

Chemical Properties

- Molecular Formula: C13H12F2O4
- Molecular Weight: 270.23 g/mol
- Melting Point: Specific melting point data is available upon request.
- Solubility: Soluble in organic solvents, including methanol and ethanol.

Quality Standards

At Ningbo Inno Pharmchem, we adhere to stringent quality control measures to ensure that our 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid meets the highest industry standards. Our product undergoes rigorous testing and analysis in compliance with guidelines, ensuring purity and efficacy for all applications.

Applications

This compound plays a pivotal role in the pharmaceutical industry, particularly as a reference substance in analytical chemistry and drug formulation. Its use extends to:

- Research and Development: As a building block in the synthesis of complex molecules and formulations.
- Quality Control: Serving as a standard for impurities in pharmaceutical products.
- Medicinal Chemistry: Useful in developing new therapeutic agents with enhanced efficacy and reduced side effects.

Synthesis Route

The synthesis of 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid typically involves several steps:

1. Formation of the cyclopropylmethoxy moiety: Using cyclopropylmethanol in a nucleophilic substitution reaction.
2. Introduction of the difluoromethoxy group: Achieved through electrophilic aromatic substitution on the benzoic acid framework.
3. Purification and isolation: Employing methods such as recrystallization or chromatography to obtain the final pure product.

Preparation Method

The preparation of this compound can be scaled according to laboratory or industrial requirements. Detailed procedural guidelines are available, ensuring the safety and efficiency of the synthesis process.

Conclusion

3-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid is a critical compound with diverse applications in the pharmaceutical sector. With our commitment to quality and innovation, Ningbo Inno Pharmchem is equipped to meet your needs with consistent product availability and support for research applications. Discover the potential of this multifaceted compound and elevate your work in drug synthesis and development.

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