Norepinephrine Bitartrate: Your Trusted Solution for Critical Care

Introduction
Norepinephrine Bitartrate, known by its various synonyms including 4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol 2,3-dihydroxysuccinate (1:1) and 4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol 2,3-dihydroxybutanedioate (1:1), is a vital medication used primarily in the treatment of severe hypotension and shock. It plays a critical role in medical settings, particularly for managing patients in intensive care units.

Chemical Properties
This compound is recognized by its CAS number 69815-49-2. Norepinephrine Bitartrate exhibits unique pharmacological properties, making it effective in increasing vascular tone and improving blood flow to vital organs. It is a potent adrenergic agonist that functions by stimulating alpha-adrenergic receptors, which facilitates vasoconstriction and elevates blood pressure.

Areas of Application
Norepinephrine Bitartrate is predominantly used in:

- Critical Care Medicine: To counteract hypotension, especially in septic shock and cardiac arrest scenarios.
- Anesthesia: As an adjunct to maintain blood pressure during surgeries and invasive procedures.
- Emergency Medicine: In managing acute cases of severe hypotension.

Quality Standards
At Ningbo Inno Pharmchem, we uphold the highest quality standards for our products. Norepinephrine Bitartrate meets rigorous pharmacopoeial specifications, ensuring safety and efficacy in medical applications.

- Purity: Regular testing ensures consistency in purity levels, adhering to the strictest pharmacopeial guidelines.
- Stability: Our formulations are engineered for maximum stability, minimizing degradation and ensuring a reliable shelf life.

Synthesis Route
The synthesis of Norepinephrine Bitartrate involves a multi-step process characterized by the careful manipulation of its key precursor compounds. Each step in the synthesis is optimized for efficiency and yield to enable the large-scale production of high-quality norepinephrine formulations.

Preparation Method
Norepinephrine Bitartrate is typically prepared as a sterile solution for intravenous infusion. The preparation involves:

1. Dissolution of Active Ingredients: Precise measurements of norepinephrine and bitartrate salts are dissolved in an appropriate sterile solvent.
2. Filtration: The solution is filtered to ensure sterility and remove any particulate matter.
3. Packaging: The final product is packaged in suitable containers under aseptic conditions.

Conclusion
Norepinephrine Bitartrate, with its proven efficacy and safety profile, is an indispensable tool in the arsenal of emergency and critical care medicine. As a leading manufacturer, Ningbo Inno Pharmchem is committed to delivering high-quality, reliable norepinephrine formulations that meet the evolving needs of healthcare professionals and their patients.

Choose Norepinephrine Bitartrate for your critical care needs, and trust in a product that prioritizes patient wellbeing and medical excellence.

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